Friday, February 8, 2008

Opportunistic Infections Upregulate CCR5 Expression

Mycobacterium avium complex augments macrophage HIV-1 production and increases CCR5 expression. It is not surprising that a serious infection should lead to greater immune activation, inflammation, and thus retroviral expression.

treating OI may inhibit not only the OI-induced pathology, but also limit the viral burden.

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