Wednesday, January 23, 2008

Stress Hormone and Viral Protein Team Up vs. Lymphocytes

HIV's glycoprotein GP120 and cortisol synergize to induce CD4 lymphocyte apoptosis.

The synergistic effect of cortisol and gp- 120 in inducing apoptosis of lymphocytes is consistent with a model proposing that stress-associated and circulating HIV-1 derived soluble products may cause progression of HIV infections.

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