Friday, January 25, 2008

HIV Infection Requires Cellular Cholesterol Rafts

Aside from cholesterol's upregulation of CCR5 and CXCR4 chemokine receptors, a study claims the virus GAG protein requires cellular cholesterol rafts for attachment to the cell.

The AIDS-causing virus, HIV, must attach to cholesterol-rich regions of a cell's membrane before it can do its destructive work, researchers at the National Institute of Allergy and Infectious Diseases (NIAID) have discovered.

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